Science.News
1.7.2024

©

Science.News
Jul 1, 2024

Modifying the DNA repair path increases CRISPR accuracy

A new, breakthrough strategy strengthens CRISPR editing, minimizes large read and delete processes, and increases the security and accuracy of genetic changes.

Source

Yuan B, BiC, Tian Y, et al. Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks. BMC Biol. 2024; 22 (1) :101. doi: 10.1186/s12915-024-01896-z