Science
ABOUT science
The biology of aging is still largely a mystery. Researchers are working hard to unravel the molecular and cellular causes of aging and to find ways to prevent age-related diseases. These discoveries, and the science that may help people stay healthy as they age, are reported here.
SCIENCE.
NEWS
26.6.2025
Factors involved in human healthy aging: Insights from longevity individuals
News
June 26, 2025
News
June 26, 2025
Factors involved in human healthy aging: Insights from longevity individuals
Longevity is the result of a combination of genetic, metabolic, immunological and lifestyle factors. The study of centenarians shows ways to healthier aging and gives hope for future measures that extend both lifespan and health span.
Quelle
Factors involved in human healthy aging: insights from longevity individuals” by Fan-Qian Yin, Fu-Hui Xiao and Qing-Peng Kong, 22 March 2025, Frontiers of Medicine. DOI: 10.1007/s11684-024-1120-4
19.6.2025
Higher daytime intake of fruits and vegetables predicts less disrupted nighttime sleep
News
June 23, 2025
News
June 23, 2025
Higher daytime intake of fruits and vegetables predicts less disrupted nighttime sleep
Higher daytime intakes of fruits and vegetables and carbohydrates that align with a healthy diet were associated with less disrupted nighttime sleep. A 5-cup increase (from no intake) in fruits and vegetables, meeting dietary recommendations, was associated with 16% better sleep quality. These findings suggest that diets rich in complex carbohydrates, fruits, and vegetables may promote better sleep health.
Quelle
Hedda L. Boege, Katherine D. Wilson, Jennifer M. Kilkus, Waveley Qiu, Bin Cheng, Kristen E. Wroblewski, Becky Tucker, Esra Tasali, Marie-Pierre St-Onge, Higher daytime intake of fruits and vegetables predicts less disrupted nighttime sleep in younger adults, Sleep Health, 2025, ISSN 2352-7218, https://doi.org/10.1016/j.sleh.2025.05.003
8.6.2025
Plasma exchange in humans lowers biological age by over two years
News
June 9, 2025
News
June 9, 2025
Plasma exchange in humans lowers biological age by over two years
In a randomized, placebo-controlled clinical trial, therapeutic plasma exchange combined with intravenous immunoglobulin reduced biological age by 2.6 years on average, as measured using multi-omics biomarkers.
Quelle
Fuentealba, M., Kiprov, D., Schneider, K., Mu, W.-C., Kumaar, P.A., Kasler, H., Burton, J.B., Watson, M., Halaweh, H., King, C.D., Yueksel, Z.S., Roska-Pamaong, C., Schilling, B., Verdin, E. and Furman, D. (2025), Multi-oman, D. Mics Analysis Reveals Biomarkers That Contribute to Biological Age Rejuvenation in Response to Single-Blinded Randomized Placebo-Controlled Therapeutic Plasma Exchange. Aging Cell e70103. https://doi.org/10.1111/acel.70103
30.5.2025
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain aging
News
May 30, 2025
News
May 30, 2025
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain aging
Exercise has a positive effect on brain health. Exciting new research shows that even brief physical activities can have a big impact on health.
Quelle
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain aging Tari, Atefe R et al. The Lancet, Volume 405, Issue 10484, 1093 - 1118
19.5.2025
Blood test predicts dementia up to 10 years in advance, study finds
News
May 19, 2025
News
May 19, 2025
Blood test predicts dementia up to 10 years in advance, study finds
A new study examined the potential of biomarkers tau217 and Neurofilament Light (NfL) to predict the onset of dementia up to ten years before clinical diagnosis in cognitively healthy older adults.
Quelle
“Blood-based biomarkers of Alzheimer's disease and incident dementia in the community” by Giulia Grande, Martina Valletta, Debora Rizzuto, Xin Xia, Chengxuan Qiu, Nicola Orsini, Matilda Dale, Sarah Andersson, Claudia Fredolini, Bengt Winblad, Erika J. Laukka, Laura Fratiglioni and Davide L. Vetrano, March 26, 2025, Nature Medicine.
SCIENCE.
EXPLAINED
Aging
Alterung
Telomeres shorten over the course of a lifetime. The normal aging process is thought to be affected by telomere shortening and thus associated with the onset of disease and increased mortality in old age.
Length
Länge
Telomeres are protective caps at the ends of chromosomes that shorten each time a cell divides. When they become so short that the genes they protect could be damaged, cells stop dividing and renewing themselves. As a result, the cells are no longer able to perform their functions. This is thought to be one of the mechanisms of aging.
Function
Funktion
Telomeres are protective caps at the ends of chromosomes that shorten each time a cell divides. When they become so short that the genes they protect could be damaged, cells stop dividing and renewing themselves. As a result, the cells become less able to perform their functions. This is thought to be one of the mechanisms of aging.
Schutz
Through prevention and proactive measures. Eating habits: high consumption of meat (especially red meat), a generally fatty diet and obesity cause the chromosome caps to wear down, as does excessive alcohol consumption. Consumption of vegetable products protects the cells.
Physical activity: Interval and endurance training can lengthen telomeres
Protetion
Science.
Quote
The goal of a genome analysis is not to find out what you will die of, but rather to learn how to prevent diseases from occurring.
George Church
American geneticist, molecular engineer, chemist, and "founder of genomics"
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