Science.News
26.7.2024

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Science.News
Jul 26, 2024

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

Scientists have found that turning off a protein called IL-11 can extend the healthy lifespan of mice by almost 25%. The researchers found that removing the IL-11 gene or using an anti-IL-11 antibody drastically increased the lifespan and health of aging mice. These findings suggest that anti-IL-11 treatments could combat age-related diseases with minimal side effects, providing a promising avenue for future human trials.

Source

Widjaja, A. A., Lim, WW., Viswanathan, S. et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature (2024). https://doi.org/10.1038/s41586-024-07701-9