The composition of the intestinal microbiome changes with age: the number of beneficial microorganisms that produce metabolites decreases, while the number of inflammatory microbes increases. In addition to these age-related changes, research suggests that the gut microbiome of people with Alzheimer's disease is significantly different from that of people without Alzheimer's disease. This points to a possible connection between the gut microbiome and the development and progression of Alzheimer's disease, even though the exact mechanisms are still unclear. Although inflammation plays an important role in Alzheimer's disease, the effects of an Alzheimer-like gut microbiome may not be solely due to increased levels of chronic inflammation compared to other older people. Further research is needed to elucidate the exact mechanisms underlying the relationship between the gut microbiome and Alzheimer's disease.