Science.News
Sep 17, 2024
New insights into epigenetic aging through single-cell analysis
A study published in Nature Aging sheds new light on the mechanisms of epigenetic aging. Based on single-cell DNA methylation data (scDNAm) from mice, the researchers classified aging processes into stochastic and co-regulated components. This classification enables a more differentiated understanding of how DNA methylation changes over the life span of an organism and may open up new avenues for targeted anti-aging measures.
Source
Tarkhov, A.E., Lindstrom-Vautrin, T., Zhang, S. et al. Nature of epigenetic aging from a single-cell perspective. Nat Aging 4, 854-870 (2024). https://doi.org/10.1038/s43587-024-00616-0
