Science.News
16.12.2025

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Science.News
Dec 16, 2025

The key molecule responsible for the anti-aging effect of sport

Systematic molecular blueprint of how exercise reshapes human homeostasis Repeated exercise boosts circulating betaine partly via renal synthesis Betaine inhibits TBK1, reducing senescence and inflammation Betaine exerts multi-organ geroprotection in aged mice

Source

Systematic profiling reveals betaine as an exercise mimetic for geroprotection Geng, Lingling et al. Cell, Volume 188, Issue 19, 5403 - 5425.e33