Science.News
16.12.2025

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Science.News
Dec 16, 2025

Super-centenarian gene should delay the onset of aging diseases

Scientists have discovered that a “longevity gene” found in people over 100 years of age can protect the heart from the effects of Progeria, a rare genetic condition that causes premature aging in children.

Source

“A longevity-associated variant of the human BPIFB4 gene prevents diastolic dysfunction in progeria mice” by Yan Qiu, Monica Cattaneo, Anna Maciag, Annibale A. Puca and Paolo Madeddu, September 29, 2025, Signal Transduction and Targeted Therapy. DOI: 10.1038/s41392-025-02416-3